Research workbench

AlphaFold monomer V2.0 prediction for tight junction protein zo-3 (O95049)

Analyse AlphaFold monomer V2.0 prediction for tight junction protein zo-3 (O95049) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: O95049
Type: protein
Length: 919 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xA528629DC5BcCeBDa9059C9f45aab2F210565E6f
Molecule: Tight junction protein zo-3
UniProt: O95049
Pockets: 9 · best druggability 0.73

Structure

1 distinct chain · 20% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tight junction protein zo-3	protein	919	20% helix, 20% strand	O95049

Pockets

9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	711	0.73	0.79	73	empty
2	159	0.55	0.81	25	empty
3	243	0.55	0.77	35	empty
4	126	0.54	0.82	22	empty
5	137	0.43	0.76	26	empty

Compared structures

3KFV · Crystal structure of the SH3-kinase fragment of tight junction protein 3 (TJP3) in… · an experimental structure of the same protein · chain A against A, TM-score 0.26
3KFV · Crystal structure of the SH3-kinase fragment of tight junction protein 3 (TJP3) in… · an experimental structure of the same protein · chain A against A, TM-score 0.26

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O95049
Elsewhere: UniProt O95049 · AlphaFold DB O95049

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.