MolNFT v1 · #541956 · protein
AlphaFold monomer V2.0 prediction for tight junction protein zo-2 (Q9UDY2)
Q9UDY2: “AlphaFold monomer V2.0 prediction for tight junction protein zo-2 (Q9UDY2)”. 5 pockets (best druggability 0.77). MolNFT v1 #541956 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9UDY2
- Type
- protein
- Length
- 1,190 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x98281d3d8CBa341522C420084261D324CBfD56d5
- Molecule
- Tight junction protein zo-2
- UniProt
- Q9UDY2
- Pockets
- 5 · best druggability 0.77
Structure
1 distinct chain · 19% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tight junction protein zo-2 | protein | 1190 | 19% helix, 15% strand | Q9UDY2 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1033 | 0.77 | 0.79 | 89 | empty |
| 2 | 457 | 0.63 | 0.76 | 41 | empty |
| 3 | 268 | 0.62 | 0.81 | 27 | empty |
| 4 | 139 | 0.40 | 0.74 | 25 | empty |
| 5 | 55 | 0.29 | 0.74 | 11 | empty |
Compared structures
- 2OSG · Solution structure and binding property of the domain-swapped dimer of ZO2PDZ2 · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2OSG · Solution Structure and Binding Property of the Domain-swapped Dimer of ZO2PDZ2 · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 3E17 · Crystal structure of the second PDZ domain from human zona occludens-2 · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 3E17 · Crystal structure of the second PDZ domain from human Zona Occludens-2 · an experimental structure of the same protein · chain A against A, TM-score 0.05
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UDY2
- Elsewhere: UniProt Q9UDY2 · AlphaFold DB Q9UDY2
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