MolNFT v1 · #541722 · protein

AlphaFold monomer V2.0 prediction for zinc transporter 1 (Q9Y6M5)

Q9Y6M5: “AlphaFold monomer V2.0 prediction for zinc transporter 1 (Q9Y6M5)”. 4 pockets (best druggability 0.78). MolNFT v1 #541722 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9Y6M5
Type: protein
Length: 507 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x3298b100681D3A2372Bba3b2f282750dD71629B9
Molecule: Zinc transporter 1
UniProt: Q9Y6M5
Pockets: 4 · best druggability 0.78

Structure

1 distinct chain · 45% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Zinc transporter 1	protein	507	45% helix, 7% strand	Q9Y6M5

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	750	0.78	0.82	61	empty
2	197	0.59	0.81	29	empty
3	61	0.49	0.85	18	empty
4	71	0.31	0.74	19	empty

Modifications

Observed in the structure: 5 disulfide (disulfide).

Compared structures

8J2G · Human ZnT1-D47N/D255N mutant · an experimental structure of the same protein · chain A against A, TM-score 0.54
8ZSB · Cryo-EM structure of human ZnT1, in the absence of zinc, determined in outward-facing… · an experimental structure of the same protein · chain A against A, TM-score 0.52

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y6M5
Elsewhere: UniProt Q9Y6M5 · AlphaFold DB Q9Y6M5

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