MolNFT v1 · #541716 · protein
AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase ZNRF3 (Q08D68)
Q08D68: “AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase ZNRF3 (Q08D68)”. 1 pocket (best druggability 0.45). MolNFT v1 #541716 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q08D68
- Type
- protein
- Length
- 853 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5881B09f2D8e743400698633641fc1cD2Ed2BE6F
- Molecule
- E3 ubiquitin-protein ligase ZNRF3
- UniProt
- Q08D68
- Pockets
- 1 · best druggability 0.45
Structure
1 distinct chain · 13% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase ZNRF3 | protein | 853 | 13% helix, 10% strand | Q08D68 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 57 | 0.45 | 0.84 | 13 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 4C9U · Xenopus ZNRF3 ectodomain in complex with xenopus RSPO2 FU1-FU2 crystal form II · an experimental structure of the same protein · chain A against A, TM-score 0.18
- 4C9U · Xenopus ZNRF3 ectodomain in complex with Xenopus RSPO2 Fu1-Fu2 crystal form II · an experimental structure of the same protein · chain A against A, TM-score 0.18
- 4C9R · Xenopus ZNRF3 ectodomain in complex with Xenopus RSPO2 Fu1-Fu2 crystal form I · an experimental structure of the same protein · chain A against A, TM-score 0.18
- 4C9R · Xenopus ZNRF3 ectodomain in complex with xenopus RSPO2 FU1- FU2 crystal form I · an experimental structure of the same protein · chain A against A, TM-score 0.18
- 4C8U · Xenopus ZNRF3 ectodomain crystal form II · an experimental structure of the same protein · chain A against A, TM-score 0.17
- 4C8U · Xenopus ZNRF3 ectodomain crystal form II · an experimental structure of the same protein · chain A against A, TM-score 0.17
- 4C8T · Xenopus ZNRF3 ectodomain crystal form I · an experimental structure of the same protein · chain A against A, TM-score 0.17
- 4C8T · Xenopus ZNRF3 ectodomain crystal form I · an experimental structure of the same protein · chain A against A, TM-score 0.17
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q08D68
- Elsewhere: UniProt Q08D68 · AlphaFold DB Q08D68
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