UniProt Q08D68
E3 ubiquitin-protein ligase ZNRF3 (Q08D68)
E3 ubiquitin-protein ligase ZNRF3 (UniProt Q08D68): 8 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q08D68
- Protein
- E3 ubiquitin-protein ligase ZNRF3
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
9 records of Q08D68 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4C8T | Xenopus ZNRF3 ectodomain crystal form I | x-ray diffraction | A, B | — | — |
| 4C8T | Xenopus ZNRF3 ectodomain crystal form I | x-ray diffraction | A, B | — | — |
| 4C8U | Xenopus ZNRF3 ectodomain crystal form II | x-ray diffraction | A, B | — | — |
| 4C8U | Xenopus ZNRF3 ectodomain crystal form II | x-ray diffraction | A, B | — | — |
| 4C9R | Xenopus ZNRF3 ectodomain in complex with Xenopus RSPO2 Fu1-Fu2 crystal form I | x-ray diffraction | A, C | — | — |
| 4C9R | Xenopus ZNRF3 ectodomain in complex with xenopus RSPO2 FU1- FU2 crystal form I | x-ray diffraction | A, C | — | — |
| 4C9U | Xenopus ZNRF3 ectodomain in complex with Xenopus RSPO2 Fu1-Fu2 crystal form II | x-ray diffraction | A, C | — | — |
| 4C9U | Xenopus ZNRF3 ectodomain in complex with xenopus RSPO2 FU1-FU2 crystal form II | x-ray diffraction | A, C | — | — |
| Q08D68 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase ZNRF3 (Q08D68) | predicted | A | — | 1 (best 0.45) |
Experiment against prediction
- 4C8U chain A against the predicted model Q08D68: TM-score 0.97, RMSD 0.79 Å
- 4C8U chain A against the predicted model Q08D68: TM-score 0.97, RMSD 0.79 Å
- 4C8T chain B against the predicted model Q08D68: TM-score 0.97, RMSD 0.80 Å
- 4C8T chain B against the predicted model Q08D68: TM-score 0.97, RMSD 0.80 Å
- 4C8U chain B against the predicted model Q08D68: TM-score 0.97, RMSD 0.82 Å
- 4C8U chain B against the predicted model Q08D68: TM-score 0.97, RMSD 0.82 Å
- 4C8T chain A against the predicted model Q08D68: TM-score 0.97, RMSD 0.83 Å
- 4C8T chain A against the predicted model Q08D68: TM-score 0.97, RMSD 0.83 Å
- 4C9U chain C against the predicted model Q08D68: TM-score 0.95, RMSD 1.43 Å
- 4C9U chain C against the predicted model Q08D68: TM-score 0.95, RMSD 1.43 Å
Elsewhere
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