MolNFT v1 · #541703 · protein

AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase ZNRF1 (Q8ND25)

Q8ND25: “AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase ZNRF1 (Q8ND25)”. 1 pocket (best druggability 0.43). MolNFT v1 #541703 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8ND25
Type: protein
Length: 227 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xd1A2963012bEcbC7A8f505464439Ab678C48936f
Molecule: E3 ubiquitin-protein ligase ZNRF1
UniProt: Q8ND25
Pockets: 1 · best druggability 0.43

Structure

1 distinct chain · 9% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	E3 ubiquitin-protein ligase ZNRF1	protein	227	9% helix, 9% strand	Q8ND25

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	127	0.43	0.76	20	empty

Compared structures

5YWR · Crystal structure of ring E3 ligase ZNRF1 in complex with UBE2N (UBC13) · an experimental structure of the same protein · chain A against B, TM-score 0.37
5YWR · Crystal Structure of RING E3 ligase ZNRF1 in complex with Ube2N (Ubc13) · an experimental structure of the same protein · chain A against B, TM-score 0.37

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8ND25
Elsewhere: UniProt Q8ND25 · AlphaFold DB Q8ND25

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