UniProt Q8ND25
E3 ubiquitin-protein ligase ZNRF1 (Q8ND25)
E3 ubiquitin-protein ligase ZNRF1 (UniProt Q8ND25), EC 2.3.2.27: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q8ND25
- Protein
- E3 ubiquitin-protein ligase ZNRF1
- EC
- 2.3.2.27
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
3 records of Q8ND25 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5YWR | Crystal Structure of RING E3 ligase ZNRF1 in complex with Ube2N (Ubc13) | x-ray diffraction | B | ZN | 1 (best 0.45) |
| 5YWR | Crystal structure of ring E3 ligase ZNRF1 in complex with UBE2N (UBC13) | x-ray diffraction | B | ZN | — |
| Q8ND25 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase ZNRF1 (Q8ND25) | predicted | A | — | 1 (best 0.43) |
Ligands
- ZN · Zinc ion · in 2 records
Experiment against prediction
- 5YWR chain B against the predicted model Q8ND25: TM-score 0.95, RMSD 1.04 Å
- 5YWR chain B against the predicted model Q8ND25: TM-score 0.95, RMSD 1.04 Å
Elsewhere
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