MolNFT v1 · #537967 · protein
AlphaFold monomer V2.0 prediction for ran-specific GTPase-activating protein 1 (P41920)
P41920: “AlphaFold monomer V2.0 prediction for ran-specific GTPase-activating protein 1 (P41920)”. 1 pocket (best druggability 0.39). MolNFT v1 #537967 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P41920
- Type
- protein
- Length
- 201 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x66026B7eDA2C7707c7042FCF1BE7d1A483c4dD3c
- Molecule
- Ran-specific GTPase-activating protein 1
- UniProt
- P41920
- Pockets
- 1 · best druggability 0.39
Structure
1 distinct chain · 12% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ran-specific GTPase-activating protein 1 | protein | 201 | 12% helix, 31% strand | P41920 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 95 | 0.39 | 0.76 | 22 | empty |
Compared structures
- 3M1I · Crystal structure of yeast CRM1 (Xpo1p) in complex with yeast RanBP1 (Yrb1p) and yeast… · an experimental structure of the same protein · chain A against B, TM-score 0.65
- 3M1I · Crystal structure of yeast CRM1 (XPO1P) in complex with yeast RANBP1 (YRB1P) and yeast… · an experimental structure of the same protein · chain A against B, TM-score 0.65
- 4HAW · Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548A)-Ran-RanBP1 · an experimental structure of the same protein · chain A against B, TM-score 0.61
- 4HAW · Crystal structure of CRM1 inhibitor leptomycin B in complex with CRM1(K548A)-ran-RANBP1 · an experimental structure of the same protein · chain A against B, TM-score 0.61
- 4HAV · Crystal structure of CRM1 inhibitor anguinomycin a in complex with CRM1-ran-RANBP1 · an experimental structure of the same protein · chain A against B, TM-score 0.61
- 4HAV · Crystal structure of CRM1 inhibitor Anguinomycin A in complex with CRM1-Ran-RanBP1 · an experimental structure of the same protein · chain A against B, TM-score 0.61
- 4HAX · Crystal structure of CRM1 inhibitor Ratjadone A in complex with CRM1(K579A)-Ran-RanBP1 · an experimental structure of the same protein · chain A against B, TM-score 0.61
- 4HAX · Crystal structure of CRM1 inhibitor ratjadone a in complex with CRM1(K579A)-ran-RANBP1 · an experimental structure of the same protein · chain A against B, TM-score 0.61
- 5YSU · Plumbagin in complex with CRM1-RANM189D-RANBP1 · an experimental structure of the same protein · chain A against B, TM-score 0.61
- 6CIT · Crystal structure of mvm NS2 nes peptide in complex with CRM1-ran- RANBP1 · an experimental structure of the same protein · chain A against B, TM-score 0.61
- 5UWS · Crystal structure of X11L2 nes peptide in complex with CRM1-ran-RANBP1 · an experimental structure of the same protein · chain A against B, TM-score 0.61
- 5UWU · Crystal structure of SMAD4 nes peptide in complex with CRM1-ran-RANBP1 · an experimental structure of the same protein · chain A against B, TM-score 0.61
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P41920
- Elsewhere: UniProt P41920 · AlphaFold DB P41920
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