UniProt P41920
Ran-specific GTPase-activating protein 1 (P41920)
Ran-specific GTPase-activating protein 1 (UniProt P41920): 101 experimental structures and 1 predicted model on GenesisL1, 80 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P41920
- Protein
- Ran-specific GTPase-activating protein 1
- Experimental structures
- 101
- Predicted models
- 1
- Pockets
- 80 · 17 records with a druggable one
Structures
102 records of P41920 in the MolNFT archive: 101 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3M1I | Crystal structure of yeast CRM1 (Xpo1p) in complex with yeast RanBP1 (Yrb1p) and yeast RanGTP… | x-ray diffraction | B | — | — |
| 3M1I | Crystal structure of yeast CRM1 (XPO1P) in complex with yeast RANBP1 (YRB1P) and yeast rangtp… | x-ray diffraction | B | — | — |
| 4GMX | Crystal structure of KPT185 in complex with CRM1-Ran-RanBP1 | x-ray diffraction | B | — | — |
| 4GMX | Crystal structure of KPT185 in complex with CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 4GPT | Crystal structure of KPT251 in complex with CRM1-Ran-RanBP1 | x-ray diffraction | B | — | — |
| 4GPT | Crystal structure of KPT251 in complex with CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 4HAT | Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1-Ran-RanBP1 | x-ray diffraction | B | — | — |
| 4HAT | Crystal structure of CRM1 inhibitor leptomycin B in complex with CRM1- ran-RANBP1 | x-ray diffraction | B | — | — |
| 4HAU | Crystal structure of CRM1 inhibitor Ratjadone A in complex with CRM1-Ran-RanBP1 | x-ray diffraction | B | — | — |
| 4HAU | Crystal structure of CRM1 inhibitor ratjadone a in complex with CRM1- ran-RANBP1 | x-ray diffraction | B | — | — |
| 4HAV | Crystal structure of CRM1 inhibitor Anguinomycin A in complex with CRM1-Ran-RanBP1 | x-ray diffraction | B | — | — |
| 4HAV | Crystal structure of CRM1 inhibitor anguinomycin a in complex with CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 4HAW | Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548A)-Ran-RanBP1 | x-ray diffraction | B | — | — |
| 4HAW | Crystal structure of CRM1 inhibitor leptomycin B in complex with CRM1(K548A)-ran-RANBP1 | x-ray diffraction | B | — | — |
| 4HAX | Crystal structure of CRM1 inhibitor Ratjadone A in complex with CRM1(K579A)-Ran-RanBP1 | x-ray diffraction | B | — | — |
| 4HAX | Crystal structure of CRM1 inhibitor ratjadone a in complex with CRM1(K579A)-ran-RANBP1 | x-ray diffraction | B | — | — |
| 4HAY | Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548E,K579Q)-Ran-RanBP1 | x-ray diffraction | B | — | — |
| 4HAY | Crystal structure of CRM1 inhibitor leptomycin B in complex with CRM1(K548E,K579Q)-ran-RANBP1 | x-ray diffraction | B | — | — |
| 4HAZ | Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(R543S,K548E,K579Q)-Ran-RanBP1 | x-ray diffraction | B | — | — |
| 4HAZ | Crystal structure of CRM1 inhibitor leptomycin B in complex with CRM1(R543S,K548E,K579Q)-ran-RANBP1 | x-ray diffraction | B | — | — |
| 4HB0 | Crystal structure of CRM1 inhibitor Leptomycin B in complex with… | x-ray diffraction | B | — | — |
| 4HB0 | Crystal structure of CRM1 inhibitor leptomycin B in complex with… | x-ray diffraction | B | — | — |
| 4HB2 | Crystal structure of CRM1-Ran-RanBP1 | x-ray diffraction | B | — | — |
| 4HB2 | Crystal structure of CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 4HB3 | Crystal structure of CRM1(T539S)-Ran-RanBP1 with weakly bound unmodeled Leptomycin B | x-ray diffraction | B | — | — |
| 4HB3 | Crystal structure of CRM1(T539S)-ran-RANBP1 with weakly bound unmodeled leptomycin B | x-ray diffraction | B | — | — |
| 4HB4 | Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(537DLTVK541/GLCEQ)-Ran-RanBP1 | x-ray diffraction | B | — | — |
| 4HB4 | Crystal structure of CRM1 inhibitor leptomycin B in complex with CRM1(537DLTVK541/GLCEQ)-ran-RANBP1 | x-ray diffraction | B | — | — |
| 4WVF | Crystal structure of KPT276 in complex with CRM1-Ran-RanBP1 | x-ray diffraction | B | — | — |
| 4WVF | Crystal structure of KPT276 in complex with CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 5DH9 | Crystal Structure of PKI NES Flip Mutant Peptide in complex with CRM1-Ran-RanBP1 | x-ray diffraction | B | — | 4 (best 0.67) |
| 5DH9 | Crystal structure of pki nes flip mutant peptide in complex with CRM1- ran-RANBP1 | x-ray diffraction | B | — | — |
| 5DHA | Crystal structure of CPEB4 nes reverse mutant peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 5DHF | Crystal structure of HRIO2 nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 5DI9 | Crystal Structure of hRio2 NES Reverse Mutant Peptide in complex with CRM1-Ran-RanBP1 | x-ray diffraction | B | — | 4 (best 0.67) |
| 5DI9 | Crystal structure of HRIO2 nes reverse mutant peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 5DIF | Crystal Structure of CPEB4 NES Peptide in complex with CRM1-Ran-RanBP1 | x-ray diffraction | B | — | 7 (best 0.53) |
| 5DIF | Crystal structure of CPEB4 nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 5JLJ | Crystal Structure of KPT8602 in complex with CRM1-Ran-RanBP1 | x-ray diffraction | B | — | — |
| 5JLJ | Crystal structure of KPT8602 in complex with CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 5UWH | Crystal Structure of Paxillin NES Peptide in complex with CRM1-Ran-RanBP1 | x-ray diffraction | B | — | — |
| 5UWH | Crystal structure of paxillin nes peptide in complex with CRM1-ran- RANBP1 | x-ray diffraction | B | — | — |
| 5UWI | Crystal Structure of HDAC5 NES Peptide in complex with CRM1-Ran-RanBP1 | x-ray diffraction | B | — | — |
| 5UWI | Crystal structure of HDAC5 nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 5UWJ | Crystal Structure of FMRP NES Peptide in complex with CRM1-Ran-RanBP1 | x-ray diffraction | B | — | 5 (best 0.65) |
| 5UWJ | Crystal structure of fmrp nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 5UWO | Crystal Structure of Engineered FMRP-1b NES Peptide in complex with CRM1-Ran-RanBP1 | x-ray diffraction | B | — | 5 (best 0.64) |
| 5UWO | Crystal structure of engineered fmrp-1B nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 5UWP | Crystal Structure of mDia2 NES Peptide in complex with CRM1-Ran-RanBP1 | x-ray diffraction | B | — | 5 (best 0.59) |
| 5UWP | Crystal structure of MDIA2 nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 5UWQ | Crystal structure of CDC7 nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 5UWR | Crystal structure of CDC7 nes peptide (extended) in complex with CRM1- ran-RANBP1 | x-ray diffraction | B | — | — |
| 5UWS | Crystal structure of X11L2 nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 5UWT | Crystal Structure of Hxk2 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1 | x-ray diffraction | B | — | — |
| 5UWT | Crystal structure of HXK2 peptide in complex with CRM1 K579A mutant- ran-RANBP1 | x-ray diffraction | B | — | — |
| 5UWU | Crystal structure of SMAD4 nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | B | — | — |
| 5UWW | Crystal structure of DEAF1 peptide in complex with CRM1 K579A mutant- ran-RANBP1 | x-ray diffraction | B | — | — |
| 5YRO | RANL182A in complex with RANBP1-CRM1 | x-ray diffraction | B | — | — |
| 5YST | RANM189D in complex with RANBP1-CRM1 | x-ray diffraction | B | — | — |
| 5YSU | Plumbagin in complex with CRM1-RANM189D-RANBP1 | x-ray diffraction | B | — | — |
42 records more on the page itself.
Experiment against prediction
- 4HAY chain B against the predicted model P41920: TM-score 0.99, RMSD 0.37 Å
- 4HAY chain B against the predicted model P41920: TM-score 0.99, RMSD 0.37 Å
- 4HAZ chain B against the predicted model P41920: TM-score 0.99, RMSD 0.37 Å
- 4HAZ chain B against the predicted model P41920: TM-score 0.99, RMSD 0.37 Å
- 4HAU chain B against the predicted model P41920: TM-score 0.99, RMSD 0.37 Å
- 4HAU chain B against the predicted model P41920: TM-score 0.99, RMSD 0.37 Å
- 4HAT chain B against the predicted model P41920: TM-score 0.99, RMSD 0.37 Å
- 4HAT chain B against the predicted model P41920: TM-score 0.99, RMSD 0.37 Å
- 4HB0 chain B against the predicted model P41920: TM-score 0.99, RMSD 0.37 Å
- 4HB0 chain B against the predicted model P41920: TM-score 0.99, RMSD 0.37 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.