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MolNFT v1 · #513940 · protein

AlphaFold monomer V2.0 prediction for uncharacterized ABC transporter ATP-binding protein TM_0288 (Q9WYC4)

Q9WYC4: “AlphaFold monomer V2.0 prediction for uncharacterized ABC transporter ATP-binding protein TM_0288 (Q9WYC4)”. 5 pockets (best druggability 0.52). MolNFT v1 #513940 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9WYC4
Type
protein
Length
598 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xD7A12721F841109403a67A62cb1740320d8999f8
Molecule
Uncharacterized ABC transporter ATP-binding protein TM_0288
UniProt
Q9WYC4
Pockets
5 · best druggability 0.52

Structure

1 distinct chain · 64% helix, 10% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AUncharacterized ABC transporter ATP-binding protein TM_0288protein59864% helix, 10% strandQ9WYC4

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12310.520.7628empty
21200.520.8020empty
31580.410.7425empty
41060.370.7421empty
5650.280.7313empty

Compared structures

  • 3QF4 · Crystal structure of a heterodimeric ABC transporter in its inward- facing conformation · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 3QF4 · Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 4Q4H · TM287/288 in its apo state · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 4Q4H · TM287/288 in its apo state · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 4Q4A · Improved model of AMP-PNP bound TM287/288 · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 4Q4A · Improved model of AMP-pnp bound TM287/288 · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 4Q4J · Structure of crosslinked TM287/288_S498C_S520C mutant · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 4Q4J · Structure of crosslinked TM287/288_S498C_S520C mutant · an experimental structure of the same protein · chain A against B, TM-score 0.92
  • 6QUZ · Structure of atpgs-bound outward-facing TM287/288 in complex with sybody SB_TM35 · an experimental structure of the same protein · chain A against B, TM-score 0.70
  • 6QUZ · Structure of ATPgS-bound outward-facing TM287/288 in complex with sybody Sb_TM35 · an experimental structure of the same protein · chain A against B, TM-score 0.70

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