MolNFT v1 · #513940 · protein
AlphaFold monomer V2.0 prediction for uncharacterized ABC transporter ATP-binding protein TM_0288 (Q9WYC4)
Q9WYC4: “AlphaFold monomer V2.0 prediction for uncharacterized ABC transporter ATP-binding protein TM_0288 (Q9WYC4)”. 5 pockets (best druggability 0.52). MolNFT v1 #513940 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9WYC4
- Type
- protein
- Length
- 598 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xD7A12721F841109403a67A62cb1740320d8999f8
- Molecule
- Uncharacterized ABC transporter ATP-binding protein TM_0288
- UniProt
- Q9WYC4
- Pockets
- 5 · best druggability 0.52
Structure
1 distinct chain · 64% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized ABC transporter ATP-binding protein TM_0288 | protein | 598 | 64% helix, 10% strand | Q9WYC4 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 231 | 0.52 | 0.76 | 28 | empty |
| 2 | 120 | 0.52 | 0.80 | 20 | empty |
| 3 | 158 | 0.41 | 0.74 | 25 | empty |
| 4 | 106 | 0.37 | 0.74 | 21 | empty |
| 5 | 65 | 0.28 | 0.73 | 13 | empty |
Compared structures
- 3QF4 · Crystal structure of a heterodimeric ABC transporter in its inward- facing conformation · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 3QF4 · Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 4Q4H · TM287/288 in its apo state · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 4Q4H · TM287/288 in its apo state · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 4Q4A · Improved model of AMP-PNP bound TM287/288 · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 4Q4A · Improved model of AMP-pnp bound TM287/288 · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 4Q4J · Structure of crosslinked TM287/288_S498C_S520C mutant · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 4Q4J · Structure of crosslinked TM287/288_S498C_S520C mutant · an experimental structure of the same protein · chain A against B, TM-score 0.92
- 6QUZ · Structure of atpgs-bound outward-facing TM287/288 in complex with sybody SB_TM35 · an experimental structure of the same protein · chain A against B, TM-score 0.70
- 6QUZ · Structure of ATPgS-bound outward-facing TM287/288 in complex with sybody Sb_TM35 · an experimental structure of the same protein · chain A against B, TM-score 0.70
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9WYC4
- Elsewhere: UniProt Q9WYC4 · AlphaFold DB Q9WYC4
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