MolNFT v1 · #498594 · protein

AlphaFold monomer V2.0 prediction for vitronectin (P22458)

P22458: “AlphaFold monomer V2.0 prediction for vitronectin (P22458)”. 7 pockets (best druggability 0.55). MolNFT v1 #498594 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P22458
Type: protein
Length: 475 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x30d872b97D5A8BBB2071246F96F833576bC307D1
Molecule: Vitronectin
UniProt: P22458
Pockets: 7 · best druggability 0.55

Structure

1 distinct chain · 14% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Vitronectin	protein	475	14% helix, 19% strand	P22458

Pockets

7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	57	0.55	0.89	19	empty
2	231	0.54	0.77	25	empty
3	115	0.50	0.80	20	empty
4	121	0.49	0.80	22	empty
5	141	0.45	0.76	23	empty

Modifications

Observed in the structure: 6 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P22458
Elsewhere: UniProt P22458 · AlphaFold DB P22458

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