MolNFT v1 · #496683 · protein
AlphaFold monomer V2.0 prediction for V-type immunoglobulin domain- containing suppressor of T-cell activation (Q9H7M9)
Q9H7M9 · V-type immunoglobulin domain-containing suppressor of…: “AlphaFold monomer V2.0 prediction for V-type immunoglobulin domain- containing suppressor of T-cell…”. 1 pocket (best druggability 0.27). MolNFT v1 #496683 on GenesisL1: 3D…
- Accession
- Q9H7M9
- Type
- protein
- Length
- 311 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xaa881a9f97666A01Da48Ea02eAe65Ad17eb8B4F6
- Molecule
- V-type immunoglobulin domain-containing suppressor of T-cell activation
- UniProt
- Q9H7M9
- Pockets
- 1 · best druggability 0.27
Structure
1 distinct chain · 24% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | V-type immunoglobulin domain-containing suppressor of T-cell activation | protein | 311 | 24% helix, 26% strand | Q9H7M9 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 63 | 0.27 | 0.73 | 16 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 8TBQ · The crystal structure of human VISTA extra cellular domain in complex with Fab fragment… · an experimental structure of the same protein · chain A against Q, TM-score 0.48
- 6OIL · Crystal structure of human vista extracellular domain · an experimental structure of the same protein · chain A against A, TM-score 0.47
- 6OIL · Crystal structure of human VISTA extracellular domain · an experimental structure of the same protein · chain A against A, TM-score 0.47
- 6U6V · Crystal structure of human PD-1H / VISTA · an experimental structure of the same protein · chain A against A, TM-score 0.46
- 6U6V · Crystal structure of human pd-1H / vista · an experimental structure of the same protein · chain A against A, TM-score 0.46
- 6MVL · Crystal structure of VISTA bound to a pH-selective antibody Fab fragment · an experimental structure of the same protein · chain A against A, TM-score 0.40
- 6MVL · Crystal structure of vista bound to a pH-selective antibody Fab fragment · an experimental structure of the same protein · chain A against A, TM-score 0.40
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H7M9
- Elsewhere: UniProt Q9H7M9 · AlphaFold DB Q9H7M9
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