UniProt Q9H7M9
V-type immunoglobulin domain-containing suppressor of T-cell activation (Q9H7M9)
V-type immunoglobulin domain-containing suppressor of T-cell activation (UniProt Q9H7M9): 7 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 9 pockets. Binding sites, druggability and experiment…
- UniProt
- Q9H7M9
- Protein
- V-type immunoglobulin domain-containing suppressor of T-cell activation
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 9 · 1 record with a druggable one
Structures
8 records of Q9H7M9 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6MVL | Crystal structure of VISTA bound to a pH-selective antibody Fab fragment | x-ray diffraction | A | NAG, SO4 | 2 (best 0.33) |
| 6MVL | Crystal structure of vista bound to a pH-selective antibody Fab fragment | x-ray diffraction | A | NAG, SO4 | — |
| 6OIL | Crystal structure of human VISTA extracellular domain | x-ray diffraction | A | NAG | — |
| 6OIL | Crystal structure of human vista extracellular domain | x-ray diffraction | A | NAG | — |
| 6U6V | Crystal structure of human PD-1H / VISTA | x-ray diffraction | A | NAG | — |
| 6U6V | Crystal structure of human pd-1H / vista | x-ray diffraction | A | NAG | — |
| 8TBQ | The crystal structure of human VISTA extra cellular domain in complex with Fab fragment of… | x-ray diffraction | P, Q | NAG | 6 (best 0.67) |
| Q9H7M9 | AlphaFold monomer V2.0 prediction for V-type immunoglobulin domain- containing suppressor of T-cell… | predicted | A | — | 1 (best 0.27) |
Ligands
Experiment against prediction
- 6OIL chain A against the predicted model Q9H7M9: TM-score 0.98, RMSD 0.64 Å
- 6OIL chain A against the predicted model Q9H7M9: TM-score 0.98, RMSD 0.64 Å
- 8TBQ chain Q against the predicted model Q9H7M9: TM-score 0.98, RMSD 0.71 Å
- 8TBQ chain P against the predicted model Q9H7M9: TM-score 0.97, RMSD 0.99 Å
- 6U6V chain A against the predicted model Q9H7M9: TM-score 0.96, RMSD 1.04 Å
- 6U6V chain A against the predicted model Q9H7M9: TM-score 0.96, RMSD 1.04 Å
- 6MVL chain A against the predicted model Q9H7M9: TM-score 0.91, RMSD 1.83 Å
- 6MVL chain A against the predicted model Q9H7M9: TM-score 0.91, RMSD 1.83 Å
Elsewhere
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