MolNFT v1 · #494981 · protein
AlphaFold monomer V2.0 prediction for V-type proton ATPase subunit S1 (Q15904)
Q15904: “AlphaFold monomer V2.0 prediction for V-type proton ATPase subunit S1 (Q15904)”. 4 pockets (best druggability 0.39). MolNFT v1 #494981 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q15904
- Type
- protein
- Length
- 470 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x084C9507B8890B44F4aE79C08a93A4457A564360
- Molecule
- V-type proton ATPase subunit S1
- UniProt
- Q15904
- Pockets
- 4 · best druggability 0.39
Structure
1 distinct chain · 26% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | V-type proton ATPase subunit S1 | protein | 470 | 26% helix, 29% strand | Q15904 |
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 96 | 0.39 | 0.75 | 15 | empty |
| 2 | 112 | 0.38 | 0.75 | 18 | empty |
| 3 | 78 | 0.32 | 0.74 | 18 | empty |
| 4 | 64 | 0.27 | 0.72 | 13 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 6WLW · The vo region of human V-ATPase in state 1 (focused refinement) · an experimental structure of the same protein · chain A against U, TM-score 0.36
- 6WLW · The Vo region of human V-ATPase in state 1 (focused refinement) · an experimental structure of the same protein · chain A against U, TM-score 0.36
- 6WM2 · Human V-ATPase in state 1 with SidK and ADP · an experimental structure of the same protein · chain A against U, TM-score 0.36
- 6WM2 · Human V-ATPase in state 1 with sidk and ADP · an experimental structure of the same protein · chain A against U, TM-score 0.36
- 7UNF · CryoEM structure of a mEAK7 bound human V-ATPase complex · an experimental structure of the same protein · chain A against s, TM-score 0.36
- 6WM4 · Human V-ATPase in state 3 with sidk and ADP · an experimental structure of the same protein · chain A against U, TM-score 0.36
- 6WM4 · Human V-ATPase in state 3 with SidK and ADP · an experimental structure of the same protein · chain A against U, TM-score 0.36
- 7U4T · Human V-ATPase in state 2 with SidK and mEAK-7 · an experimental structure of the same protein · chain A against U, TM-score 0.36
- 6WM3 · Human V-ATPase in state 2 with SidK and ADP · an experimental structure of the same protein · chain A against U, TM-score 0.36
- 6WM3 · Human V-ATPase in state 2 with sidk and ADP · an experimental structure of the same protein · chain A against U, TM-score 0.36
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15904
- Elsewhere: UniProt Q15904 · AlphaFold DB Q15904
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