MolNFT v1 · #492578 · protein
AlphaFold monomer V2.0 prediction for salivary plasminogen activator alpha 1 (P98119)
P98119: “AlphaFold monomer V2.0 prediction for salivary plasminogen activator alpha 1 (P98119)”. 6 pockets (best druggability 0.66). MolNFT v1 #492578 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P98119
- Type
- protein
- Length
- 477 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf1a8F1556714059A77767ecA75A15ac431c60971
- Molecule
- Salivary plasminogen activator alpha 1
- UniProt
- P98119
- Pockets
- 6 · best druggability 0.66
Structure
1 distinct chain · 6% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Salivary plasminogen activator alpha 1 | protein | 477 | 6% helix, 32% strand | P98119 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 138 | 0.66 | 0.88 | 25 | empty |
| 2 | 251 | 0.55 | 0.77 | 34 | empty |
| 3 | 118 | 0.54 | 0.82 | 19 | empty |
| 4 | 304 | 0.51 | 0.73 | 39 | empty |
| 5 | 144 | 0.46 | 0.77 | 28 | empty |
Modifications
Observed in the structure: 14 disulfide (disulfide).
Compared structures
- 1A5I · Catalytic domain of vampire bat (desmodus rotundus) saliva plasminogen activator in… · an experimental structure of the same protein · chain A against A, TM-score 0.55
- 1A5I · Catalytic domain of vampire bat (desmodus rotundus) saliva plasminogen activator in… · an experimental structure of the same protein · chain A against A, TM-score 0.55
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P98119
- Elsewhere: UniProt P98119 · AlphaFold DB P98119
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