MolNFT v1 · #488614 · protein

AlphaFold monomer V2.0 prediction for netrin receptor UNC5B (Q8IZJ1)

Q8IZJ1: “AlphaFold monomer V2.0 prediction for netrin receptor UNC5B (Q8IZJ1)”. 7 pockets (best druggability 0.77). MolNFT v1 #488614 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8IZJ1
Type: protein
Length: 945 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x3298b100681D3A2372Bba3b2f282750dD71629B9
Molecule: Netrin receptor UNC5B
UniProt: Q8IZJ1
Pockets: 7 · best druggability 0.77

Structure

1 distinct chain · 13% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Netrin receptor UNC5B	protein	945	13% helix, 30% strand	Q8IZJ1

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	131	0.77	0.96	27	empty
2	293	0.55	0.76	35	empty
3	228	0.48	0.75	31	empty
4	179	0.48	0.76	27	empty
5	189	0.45	0.74	33	empty

Modifications

Observed in the structure: 8 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8IZJ1
Elsewhere: UniProt Q8IZJ1 · AlphaFold DB Q8IZJ1

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