Research workbench
AlphaFold monomer V2.0 prediction for netrin receptor UNC5B (Q8IZJ1)
Analyse AlphaFold monomer V2.0 prediction for netrin receptor UNC5B (Q8IZJ1) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q8IZJ1
- Type
- protein
- Length
- 945 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x3298b100681D3A2372Bba3b2f282750dD71629B9
- Molecule
- Netrin receptor UNC5B
- UniProt
- Q8IZJ1
- Pockets
- 7 · best druggability 0.77
Structure
1 distinct chain · 13% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Netrin receptor UNC5B | protein | 945 | 13% helix, 30% strand | Q8IZJ1 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 131 | 0.77 | 0.96 | 27 | empty |
| 2 | 293 | 0.55 | 0.76 | 35 | empty |
| 3 | 228 | 0.48 | 0.75 | 31 | empty |
| 4 | 179 | 0.48 | 0.76 | 27 | empty |
| 5 | 189 | 0.45 | 0.74 | 33 | empty |
Modifications
Observed in the structure: 8 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IZJ1
- Elsewhere: UniProt Q8IZJ1 · AlphaFold DB Q8IZJ1
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