MolNFT v1 · #487021 · protein
AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 21 (Q9UK80)
Q9UK80: “AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 21 (Q9UK80)”. 3 pockets (best druggability 0.74). MolNFT v1 #487021 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9UK80
- Type
- protein
- Length
- 565 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xacC927A147a8510a9171e5fD0F68b8F54851494d
- Molecule
- Ubiquitin carboxyl-terminal hydrolase 21
- UniProt
- Q9UK80
- Pockets
- 3 · best druggability 0.74
Structure
1 distinct chain · 18% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ubiquitin carboxyl-terminal hydrolase 21 | protein | 565 | 18% helix, 17% strand | Q9UK80 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 808 | 0.74 | 0.78 | 90 | empty |
| 2 | 258 | 0.50 | 0.74 | 28 | empty |
| 3 | 61 | 0.37 | 0.79 | 15 | empty |
Compared structures
- 2Y5B · Structure of USP21 in complex with linear diubiquitin-aldehyde · an experimental structure of the same protein · chain A against E, TM-score 0.57
- 2Y5B · Structure of USP21 in complex with linear diubiquitin-aldehyde · an experimental structure of the same protein · chain A against E, TM-score 0.57
- 3MTN · USP21 in complex with a ubiquitin-based, USP21-specific inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.55
- 3MTN · Usp21 in complex with a ubiquitin-based, USP21-specific inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.55
- 3I3T · Crystal structure of covalent ubiquitin-USP21 complex · an experimental structure of the same protein · chain A against C, TM-score 0.54
- 3I3T · Crystal structure of covalent ubiquitin-USP21 complex · an experimental structure of the same protein · chain A against C, TM-score 0.54
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UK80
- Elsewhere: UniProt Q9UK80 · AlphaFold DB Q9UK80
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