MolNFT v1 · #485509 · protein

AlphaFold monomer V2.0 prediction for (E3-independent) E2 ubiquitin- conjugating enzyme (Q9C0C9)

Q9C0C9 · (E3-independent) E2 ubiquitin-conjugating enzyme: “AlphaFold monomer V2.0 prediction for (E3-independent) E2 ubiquitin- conjugating enzyme (Q9C0C9)”. 20 pockets (best druggability 0.68). MolNFT v1 #485509 on GenesisL1: 3D…

Accession: Q9C0C9
Type: protein
Length: 1,292 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xfD64dB3260CDFe4e5027DA9AEA4Ae91ce7088CaA
Molecule: (E3-independent) E2 ubiquitin-conjugating enzyme
UniProt: Q9C0C9
Pockets: 20 · best druggability 0.68

Structure

1 distinct chain · 19% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	(E3-independent) E2 ubiquitin-conjugating enzyme	protein	1292	19% helix, 20% strand	Q9C0C9

Pockets

20 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	639	0.68	0.77	61	empty
2	331	0.64	0.80	42	empty
3	476	0.64	0.77	40	empty
4	197	0.58	0.81	29	empty
5	326	0.56	0.76	29	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

7UN3 · Complex of UBE2O with NAP1L1 and ubiquitylated UL2 · an experimental structure of the same protein · chain A against A, TM-score 0.47
7UN6 · Complex of UBE2O with NAP1L1 · an experimental structure of the same protein · chain A against A, TM-score 0.46

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9C0C9
Elsewhere: UniProt Q9C0C9 · AlphaFold DB Q9C0C9

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