MolNFT v1 · #484048 · protein
AlphaFold monomer V2.0 prediction for L-tyrosine decarboxylase (J7GQ11)
J7GQ11: “AlphaFold monomer V2.0 prediction for L-tyrosine decarboxylase (J7GQ11)”. 9 pockets (best druggability 0.55). MolNFT v1 #484048 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- J7GQ11
- Type
- protein
- Length
- 626 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf87a97E0A4bB354D834857B14296240B167cbe70
- Molecule
- L-tyrosine decarboxylase
- UniProt
- J7GQ11
- Pockets
- 9 · best druggability 0.55
Structure
1 distinct chain · 50% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | L-tyrosine decarboxylase | protein | 626 | 50% helix, 13% strand | J7GQ11 |
Pockets
9 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 100 | 0.55 | 0.84 | 17 | empty |
| 2 | 136 | 0.47 | 0.78 | 29 | empty |
| 3 | 55 | 0.44 | 0.83 | 13 | empty |
| 4 | 144 | 0.39 | 0.73 | 26 | empty |
| 5 | 112 | 0.39 | 0.75 | 23 | empty |
Compared structures
- 5HSJ · Structure of tyrosine decarboxylase complex with plp at 1.9 ångströms resolution · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 5HSJ · Structure of tyrosine decarboxylase complex with PLP at 1.9 Angstroms resolution · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 5HSI · Crystal structure of tyrosine decarboxylase at 1.73 Angstroms resolution · an experimental structure of the same protein · chain A against A, TM-score 0.94
- 5HSI · Crystal structure of tyrosine decarboxylase at 1.73 ångströms resolution · an experimental structure of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt J7GQ11
- Elsewhere: UniProt J7GQ11 · AlphaFold DB J7GQ11
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