UniProt J7GQ11
Putative decarboxylase (J7GQ11)
Putative decarboxylase (UniProt J7GQ11), EC 4.1.1.25: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 38 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- J7GQ11
- Protein
- Putative decarboxylase
- EC
- 4.1.1.25
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 38 · 3 records with a druggable one
Structures
5 records of J7GQ11 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5HSI | Crystal structure of tyrosine decarboxylase at 1.73 Angstroms resolution | x-ray diffraction | A, B | MG | 17 (best 0.80) |
| 5HSI | Crystal structure of tyrosine decarboxylase at 1.73 ångströms resolution | x-ray diffraction | A, B | — | — |
| 5HSJ | Structure of tyrosine decarboxylase complex with PLP at 1.9 Angstroms resolution | x-ray diffraction | A, B | PLP | 12 (best 0.83) |
| 5HSJ | Structure of tyrosine decarboxylase complex with plp at 1.9 ångströms resolution | x-ray diffraction | A, B | — | — |
| J7GQ11 | AlphaFold monomer V2.0 prediction for L-tyrosine decarboxylase (J7GQ11) | predicted | A | — | 9 (best 0.55) |
Ligands
Experiment against prediction
- 5HSJ chain B against the predicted model J7GQ11: TM-score 0.98, RMSD 1.28 Å
- 5HSJ chain B against the predicted model J7GQ11: TM-score 0.98, RMSD 1.28 Å
- 5HSI chain B against the predicted model J7GQ11: TM-score 0.98, RMSD 1.33 Å
- 5HSI chain B against the predicted model J7GQ11: TM-score 0.98, RMSD 1.33 Å
- 5HSI chain A against the predicted model J7GQ11: TM-score 0.98, RMSD 1.37 Å
- 5HSI chain A against the predicted model J7GQ11: TM-score 0.98, RMSD 1.37 Å
- 5HSJ chain A against the predicted model J7GQ11: TM-score 0.97, RMSD 1.60 Å
- 5HSJ chain A against the predicted model J7GQ11: TM-score 0.97, RMSD 1.60 Å
Elsewhere
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