MolNFT v1 · #483819 · protein
AlphaFold monomer V2.0 prediction for tyrocidine synthase 1 (P09095)
P09095: “AlphaFold monomer V2.0 prediction for tyrocidine synthase 1 (P09095)”. 17 pockets (best druggability 0.87). MolNFT v1 #483819 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P09095
- Type
- protein
- Length
- 1,088 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x025f3b1a898b05AD2731bE6Ab72687b5920c4A3F
- Molecule
- Tyrocidine synthase 1
- UniProt
- P09095
- Pockets
- 17 · best druggability 0.87
Structure
1 distinct chain · 37% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrocidine synthase 1 | protein | 1088 | 37% helix, 22% strand | P09095 |
Pockets
17 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 453 | 0.87 | 0.94 | 74 | empty |
| 2 | 839 | 0.82 | 0.84 | 92 | empty |
| 3 | 102 | 0.66 | 0.90 | 26 | empty |
| 4 | 301 | 0.64 | 0.81 | 36 | empty |
| 5 | 264 | 0.58 | 0.78 | 39 | empty |
Compared structures
- 9BFE · Tyrocidine synthetase modules 1 and 2 crosslinked in the condensation state, complex B · an experimental structure of the same protein · chain A against A, TM-score 0.45
- 7YWK · Crystal structure of an engineered TycA variant, TycApPLA, in complex with AMP · an experimental structure of the same protein · chain A against A, TM-score 0.37
- 7YWJ · Crystal structure of an engineered TycA variant, TycA pPLA (L313P) · an experimental structure of the same protein · chain A against B, TM-score 0.36
- 5N82 · Crystal structure of an engineered tyca variant in complex with an beta-phe-AMP analog · an experimental structure of the same protein · chain A against A, TM-score 0.36
- 5N82 · Crystal structure of an engineered TycA variant in complex with an beta-Phe-AMP analog · an experimental structure of the same protein · chain A against A, TM-score 0.36
- 5N81 · Crystal structure of an engineered tyca variant in complex with an O… · an experimental structure of the same protein · chain A against A, TM-score 0.36
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09095
- Elsewhere: UniProt P09095 · AlphaFold DB P09095
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