AlphaFold monomer V2.0 prediction for huwentoxin-IV (P83303)

Structure

1 distinct chain · 40% helix, 13% strand (DSSP).

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

• 5T3M · Solution structure of a triple mutant of HwTx-IV - a potent blocker of Nav1.7 · an experimental structure of the same protein · chain A against A, TM-score 0.37
• 5T3M · Solution structure of a triple mutant of hwtx-IV - a potent blocker of NAV1.7 · an experimental structure of the same protein · chain A against A, TM-score 0.37
• 1MB6 · Three dimensional solution structure of huwentoxin-IV by 2D 1H-NMR · an experimental structure of the same protein · chain A against A, TM-score 0.37
• 1MB6 · Three dimensional solution structure of huwentoxin-IV by 2D 1H-NMR · an experimental structure of the same protein · chain A against A, TM-score 0.37
• 6W6O · NaChBac-Nav1.7VSDII chimera and HWTX-IV complex · an experimental structure of the same protein · chain A against G, TM-score 0.37
• 6W6O · Nachbac-NAV1.7VSDII chimera and hwtx-IV complex · an experimental structure of the same protein · chain A against C, TM-score 0.37
• 5TLR · Solution NMR structure of gHwTx-IV · an experimental structure of the same protein · chain A against A, TM-score 0.35
• 5TLR · Solution NMR structure of ghwtx-IV · an experimental structure of the same protein · chain A against A, TM-score 0.35
• 7K48 · Structure of NavAb/Nav1.7-VS2A chimera trapped in the resting state by tarantula toxin… · an experimental structure of the same protein · chain A against G, TM-score 0.34

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P83303
• Elsewhere: UniProt P83303 · AlphaFold DB P83303