GL1X · GenesisL1 explorer

MolNFT v1 · #482539 · protein

AlphaFold monomer V2.0 prediction for terminal uridylyltransferase 1 (Q8WQX5)

Q8WQX5: “AlphaFold monomer V2.0 prediction for terminal uridylyltransferase 1 (Q8WQX5)”. 6 pockets (best druggability 0.81). MolNFT v1 #482539 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q8WQX5
Type
protein
Length
976 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xbDA05C32aD6eE153C8C5A78dfa48d7Ba25694fea
Molecule
Terminal uridylyltransferase 1
UniProt
Q8WQX5
Pockets
6 · best druggability 0.81

Structure

1 distinct chain · 34% helix, 7% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATerminal uridylyltransferase 1protein97634% helix, 7% strandQ8WQX5

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
18380.810.8488empty
26450.690.7850empty
3940.410.7722empty
4800.360.7618empty
5570.330.7713empty

Compared structures

  • 5HZD · RNA Editing TUTase 1 from Trypanosoma brucei · an experimental structure of the same protein · chain A against A, TM-score 0.48
  • 5HZD · RNA editing tutase 1 from trypanosoma brucei · an experimental structure of the same protein · chain A against A, TM-score 0.48
  • 5IDO · RNA editing tutase 1 from trypanosoma brucei in complex with UTP · an experimental structure of the same protein · chain A against A, TM-score 0.48
  • 5IDO · RNA Editing TUTase 1 from Trypanosoma brucei in complex with UTP · an experimental structure of the same protein · chain A against A, TM-score 0.48
  • 5I49 · RNA Editing TUTase 1 from Trypanosoma brucei in complex with UTP analog UMPNPP · an experimental structure of the same protein · chain A against A, TM-score 0.48
  • 5I49 · RNA editing tutase 1 from trypanosoma brucei in complex with UTP analog umpnpp · an experimental structure of the same protein · chain A against A, TM-score 0.48

Analyse

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