MolNFT v1 · #481835 · protein
AlphaFold monomer V2.0 prediction for TELO2-interacting protein 1 homolog (O43156)
O43156: “AlphaFold monomer V2.0 prediction for TELO2-interacting protein 1 homolog (O43156)”. 8 pockets (best druggability 0.72). MolNFT v1 #481835 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O43156
- Type
- protein
- Length
- 1,089 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x362a6d063b1B7E1B6EfD3A9A7CA3612e3FE037AA
- Molecule
- TELO2-interacting protein 1 homolog
- UniProt
- O43156
- Pockets
- 8 · best druggability 0.72
Structure
1 distinct chain · 67% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | TELO2-interacting protein 1 homolog | protein | 1089 | 67% helix, 2% strand | O43156 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 762 | 0.72 | 0.78 | 62 | empty |
| 2 | 771 | 0.68 | 0.76 | 82 | empty |
| 3 | 232 | 0.50 | 0.75 | 24 | empty |
| 4 | 147 | 0.46 | 0.76 | 33 | empty |
| 5 | 128 | 0.46 | 0.77 | 17 | empty |
Compared structures
- 7F4U · Cryo-EM structure of TELO2-TTI1-TTI2 complex · an experimental structure of the same protein · chain A against B, TM-score 0.56
- 7F4U · Cryo-EM structure of TELO2-TTI1-TTI2 complex · an experimental structure of the same protein · chain A against B, TM-score 0.56
- 7OLE · Cryo-EM structure of the TELO2-TTI1-TTI2-RUVBL1-RUVBL2 complex · an experimental structure of the same protein · chain A against H, TM-score 0.52
- 7OLE · Cryo-EM structure of the TELO2-TTI1-TTI2-RUVBL1-RUVBL2 complex · an experimental structure of the same protein · chain A against H, TM-score 0.52
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43156
- Elsewhere: UniProt O43156 · AlphaFold DB O43156
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.