MolNFT v1 · #481434 · protein

AlphaFold monomer V2.0 prediction for tetratricopeptide repeat protein 7B (Q86TV6)

Q86TV6: “AlphaFold monomer V2.0 prediction for tetratricopeptide repeat protein 7B (Q86TV6)”. 11 pockets (best druggability 0.79). MolNFT v1 #481434 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q86TV6
Type: protein
Length: 843 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xd1A2963012bEcbC7A8f505464439Ab678C48936f
Molecule: Tetratricopeptide repeat protein 7B
UniProt: Q86TV6
Pockets: 11 · best druggability 0.79

Structure

1 distinct chain · 69% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tetratricopeptide repeat protein 7B	protein	843	69% helix, 0% strand	Q86TV6

Pockets

11 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	777	0.79	0.82	62	empty
2	501	0.69	0.79	47	empty
3	353	0.67	0.81	43	empty
4	443	0.65	0.78	48	empty
5	236	0.60	0.80	32	empty

Compared structures

6BQ1 · Human PI4KIIIa lipid kinase complex · an experimental structure of the same protein · chain A against B, TM-score 0.80
6BQ1 · Human PI4KIIIA lipid kinase complex · an experimental structure of the same protein · chain A against B, TM-score 0.80
5DSE · Crystal structure of the TTC7B/HYCCIN complex · an experimental structure of the same protein · chain A against C, TM-score 0.80

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q86TV6
Elsewhere: UniProt Q86TV6 · AlphaFold DB Q86TV6

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