MolNFT v1 · #481039 · protein
AlphaFold monomer V2.0 prediction for tetraspanin-15 (O95858)
O95858: “AlphaFold monomer V2.0 prediction for tetraspanin-15 (O95858)”. 4 pockets (best druggability 0.52). MolNFT v1 #481039 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O95858
- Type
- protein
- Length
- 294 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0D671490EE06E75975e90D7F99F73B20BE618744
- Molecule
- Tetraspanin-15
- UniProt
- O95858
- Pockets
- 4 · best druggability 0.52
Structure
1 distinct chain · 67% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tetraspanin-15 | protein | 294 | 67% helix, 1% strand | O95858 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 262 | 0.52 | 0.74 | 31 | empty |
| 2 | 111 | 0.51 | 0.81 | 17 | empty |
| 3 | 108 | 0.42 | 0.77 | 22 | empty |
| 4 | 97 | 0.33 | 0.73 | 14 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 8ESV · Structure of human ADAM10-Tspan15 complex bound to 11G2 vFab · an experimental structure of the same protein · chain A against B, TM-score 0.81
- 7RDB · Crystal structure of Tspan15 large extracellular loop (Tspan15 LEL) · an experimental structure of the same protein · chain A against E, TM-score 0.40
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O95858
- Elsewhere: UniProt O95858 · AlphaFold DB O95858
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