UniProt O95858
Tetraspanin-15 (O95858)
Tetraspanin-15 (UniProt O95858): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 36 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O95858
- Protein
- Tetraspanin-15
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 36 · 3 records with a druggable one
Structures
6 records of O95858 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7RD5 | Crystal structure of Tspan15 large extracellular loop (Tspan15 LEL) in complex with 1C12 Fab | x-ray diffraction | F, E | — | 6 (best 0.46) |
| 7RD5 | Crystal structure of TSPAN15 large extracellular loop (TSPAN15 lel) in complex with 1C12 Fab | x-ray diffraction | F, E | — | — |
| 7RDB | Crystal structure of Tspan15 large extracellular loop (Tspan15 LEL) | x-ray diffraction | B, A, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | — | 20 (best 0.80) |
| 7RDB | Crystal structure of TSPAN15 large extracellular loop (TSPAN15 lel) | x-ray diffraction | B, A, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | — | — |
| 8ESV | Structure of human ADAM10-Tspan15 complex bound to 11G2 vFab | electron microscopy | B | Y01 | 6 (best 0.62) |
| O95858 | AlphaFold monomer V2.0 prediction for tetraspanin-15 (O95858) | predicted | A | — | 4 (best 0.52) |
Ligands
- Y01 · Cholesterol hemisuccinate · in 1 record
Experiment against prediction
- 7RDB chain V against the predicted model O95858: TM-score 0.94, RMSD 1.23 Å
- 7RDB chain V against the predicted model O95858: TM-score 0.94, RMSD 1.23 Å
- 7RDB chain D against the predicted model O95858: TM-score 0.93, RMSD 1.42 Å
- 7RDB chain D against the predicted model O95858: TM-score 0.93, RMSD 1.42 Å
- 7RDB chain E against the predicted model O95858: TM-score 0.93, RMSD 1.45 Å
- 8ESV chain B against the predicted model O95858: TM-score 0.93, RMSD 1.68 Å
- 7RDB chain H against the predicted model O95858: TM-score 0.93, RMSD 1.52 Å
- 7RDB chain I against the predicted model O95858: TM-score 0.93, RMSD 1.55 Å
- 7RDB chain K against the predicted model O95858: TM-score 0.93, RMSD 1.51 Å
- 7RDB chain S against the predicted model O95858: TM-score 0.93, RMSD 1.58 Å
Elsewhere
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