GL1X · GenesisL1 explorer

MolNFT v1 · #479413 · protein

AlphaFold monomer V2.0 prediction for tRNA pseudouridine synthase B (Q9WZW0)

Q9WZW0: “AlphaFold monomer V2.0 prediction for tRNA pseudouridine synthase B (Q9WZW0)”. 1 pocket (best druggability 0.66). MolNFT v1 #479413 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9WZW0
Type
protein
Length
309 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9B130d619fCFc21d0D08E5Ce38Cf42A5fbe230CB
Molecule
TRNA pseudouridine synthase B
UniProt
Q9WZW0
Pockets
1 · best druggability 0.66

Structure

1 distinct chain · 25% helix, 37% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATRNA pseudouridine synthase Bprotein30925% helix, 37% strandQ9WZW0

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13320.660.8037empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

  • 1R3E · Crystal Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA-protein… · an experimental structure of the same protein · chain A against A, TM-score 0.98
  • 1R3E · Crystal structure of tRNA pseudouridine synthase trub and its RNA complex: RNA-protein… · an experimental structure of the same protein · chain A against A, TM-score 0.98
  • 2AB4 · Dissecting the Roles of a Strictly Conserved Tyrosine in Substrate Recognition and… · an experimental structure of the same protein · chain A against A, TM-score 0.96
  • 2AB4 · Dissecting the roles of a strictly conserved tyrosine in substrate recognition and… · an experimental structure of the same protein · chain A against A, TM-score 0.96
  • 1ZE2 · Conformational change of pseudouridine 55 synthase upon its association with RNA substrate · an experimental structure of the same protein · chain A against A, TM-score 0.95
  • 1ZE2 · Conformational change of pseudouridine 55 synthase upon its association with RNA substrate · an experimental structure of the same protein · chain A against A, TM-score 0.95
  • 1ZE1 · Conformational change of pseudouridine 55 synthase upon its association with RNA substrate · an experimental structure of the same protein · chain A against A, TM-score 0.92
  • 1ZE1 · Conformational Change of Pseudouridine 55 Synthase upon Its Association with RNA Substrate · an experimental structure of the same protein · chain A against A, TM-score 0.92

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