UniProt Q9WZW0
tRNA pseudouridine synthase B (Q9WZW0)
tRNA pseudouridine synthase B (UniProt Q9WZW0), EC 4.2.1.70, 5.4.99.-: 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 26 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9WZW0
- Protein
- tRNA pseudouridine synthase B
- EC
- 4.2.1.70, 5.4.99.-
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 26 · 4 records with a druggable one
Structures
9 records of Q9WZW0 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1R3E | Crystal Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA-protein Recognition… | x-ray diffraction | A | — | 4 (best 0.72) |
| 1R3E | Crystal structure of tRNA pseudouridine synthase trub and its RNA complex: RNA-protein recognition… | x-ray diffraction | A | — | — |
| 1ZE1 | Conformational Change of Pseudouridine 55 Synthase upon Its Association with RNA Substrate | x-ray diffraction | A, B, C, D | MG | 12 (best 0.58) |
| 1ZE1 | Conformational change of pseudouridine 55 synthase upon its association with RNA substrate | x-ray diffraction | A, B, C, D | — | — |
| 1ZE2 | Conformational change of pseudouridine 55 synthase upon its association with RNA substrate | x-ray diffraction | A, B | — | 5 (best 0.78) |
| 1ZE2 | Conformational change of pseudouridine 55 synthase upon its association with RNA substrate | x-ray diffraction | A, B | — | — |
| 2AB4 | Dissecting the Roles of a Strictly Conserved Tyrosine in Substrate Recognition and Catalysis by… | x-ray diffraction | A | ZN | 4 (best 0.49) |
| 2AB4 | Dissecting the roles of a strictly conserved tyrosine in substrate recognition and catalysis by… | x-ray diffraction | A | — | — |
| Q9WZW0 | AlphaFold monomer V2.0 prediction for tRNA pseudouridine synthase B (Q9WZW0) | predicted | A | — | 1 (best 0.66) |
Ligands
Experiment against prediction
- 1ZE1 chain D against the predicted model Q9WZW0: TM-score 0.99, RMSD 0.68 Å
- 1ZE1 chain D against the predicted model Q9WZW0: TM-score 0.99, RMSD 0.68 Å
- 1R3E chain A against the predicted model Q9WZW0: TM-score 0.99, RMSD 0.73 Å
- 1R3E chain A against the predicted model Q9WZW0: TM-score 0.99, RMSD 0.73 Å
- 2AB4 chain A against the predicted model Q9WZW0: TM-score 0.99, RMSD 0.71 Å
- 2AB4 chain A against the predicted model Q9WZW0: TM-score 0.99, RMSD 0.71 Å
- 1ZE2 chain A against the predicted model Q9WZW0: TM-score 0.98, RMSD 0.90 Å
- 1ZE2 chain A against the predicted model Q9WZW0: TM-score 0.98, RMSD 0.90 Å
- 1ZE2 chain B against the predicted model Q9WZW0: TM-score 0.98, RMSD 0.83 Å
- 1ZE2 chain B against the predicted model Q9WZW0: TM-score 0.98, RMSD 0.83 Å
Elsewhere
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