MolNFT v1 · #476753 · protein

AlphaFold monomer V2.0 prediction for short transient receptor potential channel 6 (Q61143)

Q61143: “AlphaFold monomer V2.0 prediction for short transient receptor potential channel 6 (Q61143)”. 12 pockets (best druggability 0.78). MolNFT v1 #476753 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q61143
Type: protein
Length: 930 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x46EfCa788d03A3e879DAcDb96552AB8Bbc7e20b3
Molecule: Short transient receptor potential channel 6
UniProt: Q61143
Pockets: 12 · best druggability 0.78

Structure

1 distinct chain · 63% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Short transient receptor potential channel 6	protein	930	63% helix, 0% strand	Q61143

Pockets

12 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1117	0.78	0.80	72	empty
2	251	0.65	0.82	28	empty
3	340	0.62	0.78	26	empty
4	320	0.53	0.74	31	empty
5	180	0.48	0.76	27	empty

Compared structures

6CV9 · Cytoplasmic domain of mTRPC6 · an experimental structure of the same protein · chain A against A, TM-score 0.33
6CV9 · Cytoplasmic domain of MTRPC6 · an experimental structure of the same protein · chain A against A, TM-score 0.33

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q61143
Elsewhere: UniProt Q61143 · AlphaFold DB Q61143

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