MolNFT v1 · #473563 · protein
AlphaFold monomer V2.0 prediction for tRNA (uracil-5-)-methyltransferase homolog a (Q8IZ69)
Q8IZ69: “AlphaFold monomer V2.0 prediction for tRNA (uracil-5-)-methyltransferase homolog a (Q8IZ69)”. 4 pockets (best druggability 0.65). MolNFT v1 #473563 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8IZ69
- Type
- protein
- Length
- 625 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7782F4817b37743d738e9aF842bf74bd50f2015E
- Molecule
- TRNA (uracil-5-)-methyltransferase homolog a
- UniProt
- Q8IZ69
- Pockets
- 4 · best druggability 0.65
Structure
1 distinct chain · 28% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | TRNA (uracil-5-)-methyltransferase homolog a | protein | 625 | 28% helix, 20% strand | Q8IZ69 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 606 | 0.65 | 0.76 | 64 | empty |
| 2 | 403 | 0.61 | 0.76 | 31 | empty |
| 3 | 310 | 0.52 | 0.74 | 41 | empty |
| 4 | 69 | 0.39 | 0.79 | 21 | empty |
Compared structures
- 7NTN · The structure of rrm domain of human TRMT2A at 2 a resolution · an experimental structure of the same protein · chain A against A, TM-score 0.12
- 7NTO · The structure of rrm domain of human TRMT2A at 1.23 a resolution · an experimental structure of the same protein · chain A against A, TM-score 0.12
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IZ69
- Elsewhere: UniProt Q8IZ69 · AlphaFold DB Q8IZ69
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