MolNFT v1 · #473266 · protein
AlphaFold monomer V2.0 prediction for tripartite motif-containing protein 65 (Q6PJ69)
Q6PJ69: “AlphaFold monomer V2.0 prediction for tripartite motif-containing protein 65 (Q6PJ69)”. 3 pockets (best druggability 0.39). MolNFT v1 #473266 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6PJ69
- Type
- protein
- Length
- 517 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x08f1B0edc8474cb3B0f88330111598d367318E80
- Molecule
- Tripartite motif-containing protein 65
- UniProt
- Q6PJ69
- Pockets
- 3 · best druggability 0.39
Structure
1 distinct chain · 35% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tripartite motif-containing protein 65 | protein | 517 | 35% helix, 19% strand | Q6PJ69 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 107 | 0.39 | 0.75 | 24 | empty |
| 2 | 107 | 0.37 | 0.74 | 20 | empty |
| 3 | 74 | 0.31 | 0.74 | 16 | empty |
Compared structures
- 7JL4 · Crystal structure of TRIM65 pspry domain · an experimental structure of the same protein · chain A against A, TM-score 0.36
- 7JL4 · Crystal structure of TRIM65 PSpry domain · an experimental structure of the same protein · chain A against A, TM-score 0.36
- 7JL2 · Cryo-EM structure of MDA5-dsrna filament in complex with TRIM65 pspry domain (trimer) · an experimental structure of the same protein · chain A against B, TM-score 0.34
- 7JL0 · Cryo-EM structure of MDA5-dsrna in complex with TRIM65 pspry domain (monomer) · an experimental structure of the same protein · chain A against B, TM-score 0.34
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6PJ69
- Elsewhere: UniProt Q6PJ69 · AlphaFold DB Q6PJ69
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