UniProt Q6PJ69
Tripartite motif-containing protein 65 (Q6PJ69)
Tripartite motif-containing protein 65 (UniProt Q6PJ69): 4 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6PJ69
- Protein
- Tripartite motif-containing protein 65
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 3 · 0 records with a druggable one
Structures
5 records of Q6PJ69 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7JL0 | Cryo-EM structure of MDA5-dsrna in complex with TRIM65 pspry domain (monomer) | electron microscopy | B | — | — |
| 7JL2 | Cryo-EM structure of MDA5-dsrna filament in complex with TRIM65 pspry domain (trimer) | electron microscopy | B, D, F | — | — |
| 7JL4 | Crystal structure of TRIM65 PSpry domain | x-ray diffraction | A, C, B | — | — |
| 7JL4 | Crystal structure of TRIM65 pspry domain | x-ray diffraction | A, C, B | — | — |
| Q6PJ69 | AlphaFold monomer V2.0 prediction for tripartite motif-containing protein 65 (Q6PJ69) | predicted | A | — | 3 (best 0.39) |
Experiment against prediction
- 7JL4 chain B against the predicted model Q6PJ69: TM-score 0.98, RMSD 0.93 Å
- 7JL4 chain B against the predicted model Q6PJ69: TM-score 0.98, RMSD 0.93 Å
- 7JL2 chain B against the predicted model Q6PJ69: TM-score 0.97, RMSD 0.92 Å
- 7JL4 chain C against the predicted model Q6PJ69: TM-score 0.97, RMSD 1.03 Å
- 7JL4 chain C against the predicted model Q6PJ69: TM-score 0.97, RMSD 1.03 Å
- 7JL0 chain B against the predicted model Q6PJ69: TM-score 0.97, RMSD 0.93 Å
- 7JL4 chain A against the predicted model Q6PJ69: TM-score 0.96, RMSD 0.91 Å
- 7JL4 chain A against the predicted model Q6PJ69: TM-score 0.96, RMSD 0.91 Å
Elsewhere
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