MolNFT v1 · #473234 · protein

AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase TRIM58 (Q8NG06)

Q8NG06: “AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase TRIM58 (Q8NG06)”. 1 pocket (best druggability 0.41). MolNFT v1 #473234 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8NG06
Type: protein
Length: 486 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7310fDaCcE7C999c7cdBFc084e684F0357D79621
Molecule: E3 ubiquitin-protein ligase TRIM58
UniProt: Q8NG06
Pockets: 1 · best druggability 0.41

Structure

1 distinct chain · 36% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	E3 ubiquitin-protein ligase TRIM58	protein	486	36% helix, 20% strand	Q8NG06

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	143	0.41	0.74	25	empty

Compared structures

8PD4 · Crystal structure of TRIM58 PRY-SPRY domain · an experimental structure of the same protein · chain A against A, TM-score 0.37
8PD6 · Crystal structure of the TRIM58 PRY-SPRY domain in complex with TRIM-473 · an experimental structure of the same protein · chain A against A, TM-score 0.36

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8NG06
Elsewhere: UniProt Q8NG06 · AlphaFold DB Q8NG06

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