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UniProt Q8NG06

E3 ubiquitin-protein ligase TRIM58 (Q8NG06)

E3 ubiquitin-protein ligase TRIM58 (UniProt Q8NG06), EC 2.3.2.27: 1 experimental structure and 1 predicted model on GenesisL1, 3 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in…

UniProt
Q8NG06
Protein
E3 ubiquitin-protein ligase TRIM58
EC
2.3.2.27
Experimental structures
1
Predicted models
1
Ligands
3
Pockets
1 · 0 records with a druggable one

Structures

2 records of Q8NG06 in the MolNFT archive: 1 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
8PD6Crystal structure of the TRIM58 PRY-SPRY domain in complex with TRIM-473x-ray diffractionAYCB, MG, CL—
Q8NG06AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase TRIM58 (Q8NG06)predictedA—1 (best 0.41)

Ligands

  • CL · Chloride ion · in 1 record
  • MG · Magnesium ion · in 1 record
  • YCB · ~{N}2-[3-(dimethylamino)propyl]-6-phenyl-~{N}4-(piperidin-4-ylmethyl)quinazoline-2,4-diamine · in 1 record

Experiment against prediction

Elsewhere

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