MolNFT v1 · #472206 · protein

AlphaFold monomer V2.0 prediction for TNF receptor-associated factor 1 (Q13077)

Q13077: “AlphaFold monomer V2.0 prediction for TNF receptor-associated factor 1 (Q13077)”. 3 pockets (best druggability 0.58). MolNFT v1 #472206 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q13077
Type: protein
Length: 416 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x0C565B44183A2EdEAd47c93586302667F007a919
Molecule: TNF receptor-associated factor 1
UniProt: Q13077
Pockets: 3 · best druggability 0.58

Structure

1 distinct chain · 38% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	TNF receptor-associated factor 1	protein	416	38% helix, 15% strand	Q13077

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	328	0.58	0.76	32	empty
2	178	0.45	0.75	21	empty
3	59	0.35	0.78	18	empty

Compared structures

5H10 · TRAF1-TANk complex · an experimental structure of the same protein · chain A against C, TM-score 0.46
5H10 · TRAF1-tank complex · an experimental structure of the same protein · chain A against C, TM-score 0.46
5E1T · Crystal structure of TRAF1 traf domain · an experimental structure of the same protein · chain A against B, TM-score 0.45
5E1T · Crystal structure of TRAF1 TRAF domain · an experimental structure of the same protein · chain A against B, TM-score 0.45

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q13077
Elsewhere: UniProt Q13077 · AlphaFold DB Q13077

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