MolNFT v1 · #470721 · protein
AlphaFold monomer V2.0 prediction for triosephosphate isomerase, cytosolic (P48491)
P48491: “AlphaFold monomer V2.0 prediction for triosephosphate isomerase, cytosolic (P48491)”. 3 pockets (best druggability 0.36). MolNFT v1 #470721 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P48491
- Type
- protein
- Length
- 254 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd1A2963012bEcbC7A8f505464439Ab678C48936f
- Molecule
- Triosephosphate isomerase, cytosolic
- UniProt
- P48491
- Pockets
- 3 · best druggability 0.36
Structure
1 distinct chain · 45% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Triosephosphate isomerase, cytosolic | protein | 254 | 45% helix, 15% strand | P48491 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 81 | 0.36 | 0.76 | 20 | empty |
| 2 | 67 | 0.34 | 0.76 | 14 | empty |
| 3 | 50 | 0.29 | 0.76 | 16 | empty |
Compared structures
- 6NXW · Crystal structure of arabidopsis thaliana cytosolic triosephosphate isomerase C218S mutant · an experimental structure of the same protein · chain A against C, TM-score 0.99
- 6NXY · Crystal structure of arabidopsis thaliana cytosolic triosephosphate isomerase C218D mutant · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 4OBT · Crystal structure of Arabidopsis thaliana cytosolic triose phosphate isomerase · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 4OBT · Crystal structure of arabidopsis thaliana cytosolic triose phosphate isomerase · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 6NXQ · Crystal structure of arabidopsis thaliana cytosolic triosephosphate isomerase C13A mutant · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 6NXQ · Crystal structure of Arabidopsis thaliana cytosolic triosephosphate isomerase C13A mutant · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 6NXX · Crystal structure of Arabidopsis thaliana cytosolic triosephosphate isomerase C218K mutant · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 6NXX · Crystal structure of arabidopsis thaliana cytosolic triosephosphate isomerase C218K mutant · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 6NXR · Crystal structure of arabidopsis thaliana cytosolic triosephosphate isomerase C13D mutant · an experimental structure of the same protein · chain A against A, TM-score 0.97
- 6NXS · Crystal structure of arabidopsis thaliana cytosolic triosephosphate isomerase C218Y mutant · an experimental structure of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P48491
- Elsewhere: UniProt P48491 · AlphaFold DB P48491
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