MolNFT v1 · #470051 · protein

AlphaFold monomer V2.0 prediction for DNA topoisomerase 3 (Q5WAX6)

Q5WAX6: “AlphaFold monomer V2.0 prediction for DNA topoisomerase 3 (Q5WAX6)”. 6 pockets (best druggability 0.73). MolNFT v1 #470051 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q5WAX6
Type: protein
Length: 729 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xf87a97E0A4bB354D834857B14296240B167cbe70
Molecule: DNA topoisomerase 3
UniProt: Q5WAX6
Pockets: 6 · best druggability 0.73

Structure

1 distinct chain · 43% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA topoisomerase 3	protein	729	43% helix, 21% strand	Q5WAX6

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	844	0.73	0.78	72	empty
2	107	0.57	0.85	30	empty
3	252	0.53	0.76	28	empty
4	139	0.37	0.73	28	empty
5	64	0.33	0.76	16	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5WAX6
Elsewhere: UniProt Q5WAX6 · AlphaFold DB Q5WAX6

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