Research workbench
AlphaFold monomer V2.0 prediction for DNA topoisomerase 3 (Q5WAX6)
Analyse AlphaFold monomer V2.0 prediction for DNA topoisomerase 3 (Q5WAX6) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q5WAX6
- Type
- protein
- Length
- 729 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf87a97E0A4bB354D834857B14296240B167cbe70
- Molecule
- DNA topoisomerase 3
- UniProt
- Q5WAX6
- Pockets
- 6 · best druggability 0.73
Structure
1 distinct chain · 43% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA topoisomerase 3 | protein | 729 | 43% helix, 21% strand | Q5WAX6 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 844 | 0.73 | 0.78 | 72 | empty |
| 2 | 107 | 0.57 | 0.85 | 30 | empty |
| 3 | 252 | 0.53 | 0.76 | 28 | empty |
| 4 | 139 | 0.37 | 0.73 | 28 | empty |
| 5 | 64 | 0.33 | 0.76 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5WAX6
- Elsewhere: UniProt Q5WAX6 · AlphaFold DB Q5WAX6
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