MolNFT v1 · #469304 · protein
AlphaFold monomer V2.0 prediction for tumor necrosis factor receptor superfamily member 6 (P25446)
P25446: “AlphaFold monomer V2.0 prediction for tumor necrosis factor receptor superfamily member 6 (P25446)”. 1 pocket (best druggability 0.31). MolNFT v1 #469304 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P25446
- Type
- protein
- Length
- 327 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf849160D6081641c43ABA768B2b1C10AD3F94E20
- Molecule
- Tumor necrosis factor receptor superfamily member 6
- UniProt
- P25446
- Pockets
- 1 · best druggability 0.31
Structure
1 distinct chain · 35% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tumor necrosis factor receptor superfamily member 6 | protein | 327 | 35% helix, 13% strand | P25446 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 52 | 0.31 | 0.76 | 11 | empty |
Modifications
Observed in the structure: 10 disulfide (disulfide).
Compared structures
- 3OQ9 · Structure of the FAS/FADD death domain assembly · an experimental structure of the same protein · chain A against A, TM-score 0.24
- 3OQ9 · Structure of the FAS/FADD death domain assembly · an experimental structure of the same protein · chain A against A, TM-score 0.24
- 2NA6 · Transmembrane domain of mouse Fas/CD95 death receptor · an experimental structure of the same protein · chain A against A, TM-score 0.07
- 2NA6 · Transmembrane domain of mouse FAS/CD95 death receptor · an experimental structure of the same protein · chain A against A, TM-score 0.07
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P25446
- Elsewhere: UniProt P25446 · AlphaFold DB P25446
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