MolNFT v1 · #469275 · protein
AlphaFold monomer V2.0 prediction for thiamine pyrophosphokinase (P41888)
P41888: “AlphaFold monomer V2.0 prediction for thiamine pyrophosphokinase (P41888)”. 6 pockets (best druggability 0.74). MolNFT v1 #469275 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P41888
- Type
- protein
- Length
- 569 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5c4adF1416281C09AE8eE1cbb80fF7e44cE86F97
- Molecule
- Thiamine pyrophosphokinase
- UniProt
- P41888
- Pockets
- 6 · best druggability 0.74
Structure
1 distinct chain · 28% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thiamine pyrophosphokinase | protein | 569 | 28% helix, 29% strand | P41888 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 480 | 0.74 | 0.83 | 44 | empty |
| 2 | 515 | 0.61 | 0.74 | 52 | empty |
| 3 | 184 | 0.54 | 0.79 | 27 | empty |
| 4 | 100 | 0.46 | 0.80 | 23 | empty |
| 5 | 50 | 0.33 | 0.78 | 14 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P41888
- Elsewhere: UniProt P41888 · AlphaFold DB P41888
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