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AlphaFold monomer V2.0 prediction for thiamine pyrophosphokinase (P41888)

Analyse AlphaFold monomer V2.0 prediction for thiamine pyrophosphokinase (P41888) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P41888
Type
protein
Length
569 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x5c4adF1416281C09AE8eE1cbb80fF7e44cE86F97
Molecule
Thiamine pyrophosphokinase
UniProt
P41888
Pockets
6 · best druggability 0.74

Structure

1 distinct chain · 28% helix, 29% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AThiamine pyrophosphokinaseprotein56928% helix, 29% strandP41888

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14800.740.8344empty
25150.610.7452empty
31840.540.7927empty
41000.460.8023empty
5500.330.7814empty

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