MolNFT v1 · #469249 · protein
AlphaFold monomer V2.0 prediction for tumor necrosis factor receptor superfamily member 18 (O35714)
O35714: “AlphaFold monomer V2.0 prediction for tumor necrosis factor receptor superfamily member 18 (O35714)”. 1 pocket (best druggability 0.30). MolNFT v1 #469249 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O35714
- Type
- protein
- Length
- 228 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x3a46cFc9847C4DE8A6F058d476de545886284659
- Molecule
- Tumor necrosis factor receptor superfamily member 18
- UniProt
- O35714
- Pockets
- 1 · best druggability 0.30
Structure
1 distinct chain · 26% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tumor necrosis factor receptor superfamily member 18 | protein | 228 | 26% helix, 19% strand | O35714 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 71 | 0.30 | 0.73 | 15 | empty |
Modifications
Observed in the structure: 7 disulfide (disulfide).
Compared structures
- 7RFP · Mouse gitr (mgitr) with dta-1 Fab fragment · an experimental structure of the same protein · chain A against A, TM-score 0.45
- 7KHX · Mouse gitr-gitrl complex · an experimental structure of the same protein · chain A against D, TM-score 0.43
- 7E57 · Crystal structure of murine gitr-gitrl complex · an experimental structure of the same protein · chain A against C, TM-score 0.40
- 7E57 · Crystal structure of murine GITR-GITRL complex · an experimental structure of the same protein · chain A against C, TM-score 0.40
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O35714
- Elsewhere: UniProt O35714 · AlphaFold DB O35714
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