UniProt O35714
Tumor necrosis factor receptor superfamily member 18 (O35714)
Tumor necrosis factor receptor superfamily member 18 (UniProt O35714): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction…
- UniProt
- O35714
- Protein
- Tumor necrosis factor receptor superfamily member 18
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 1 · 0 records with a druggable one
Structures
5 records of O35714 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7E57 | Crystal structure of murine GITR-GITRL complex | x-ray diffraction | C, D | NAG, FUC | — |
| 7E57 | Crystal structure of murine gitr-gitrl complex | x-ray diffraction | C, D | NAG, FUC | — |
| 7KHX | Mouse gitr-gitrl complex | x-ray diffraction | D, C | NAG | — |
| 7RFP | Mouse gitr (mgitr) with dta-1 Fab fragment | electron microscopy | A, B | — | — |
| O35714 | AlphaFold monomer V2.0 prediction for tumor necrosis factor receptor superfamily member 18 (O35714) | predicted | A | — | 1 (best 0.30) |
Ligands
Experiment against prediction
- 7E57 chain D against the predicted model O35714: TM-score 0.87, RMSD 1.68 Å
- 7E57 chain D against the predicted model O35714: TM-score 0.87, RMSD 1.68 Å
- 7KHX chain D against the predicted model O35714: TM-score 0.86, RMSD 1.90 Å
- 7KHX chain C against the predicted model O35714: TM-score 0.85, RMSD 1.82 Å
- 7RFP chain A against the predicted model O35714: TM-score 0.82, RMSD 2.20 Å
- 7E57 chain C against the predicted model O35714: TM-score 0.76, RMSD 2.40 Å
- 7E57 chain C against the predicted model O35714: TM-score 0.76, RMSD 2.40 Å
Elsewhere
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