MolNFT v1 · #469230 · protein
AlphaFold monomer V2.0 prediction for transportin-3 (Q9Y5L0)
Q9Y5L0: “AlphaFold monomer V2.0 prediction for transportin-3 (Q9Y5L0)”. 7 pockets (best druggability 0.54). MolNFT v1 #469230 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9Y5L0
- Type
- protein
- Length
- 923 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x79a905d858Ce72991FD6E7a9C6498620f42E146D
- Molecule
- Transportin-3
- UniProt
- Q9Y5L0
- Pockets
- 7 · best druggability 0.54
Structure
1 distinct chain · 77% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transportin-3 | protein | 923 | 77% helix, 0% strand | Q9Y5L0 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 172 | 0.54 | 0.79 | 26 | empty |
| 2 | 164 | 0.50 | 0.78 | 24 | empty |
| 3 | 57 | 0.47 | 0.84 | 19 | empty |
| 4 | 97 | 0.39 | 0.76 | 18 | empty |
| 5 | 56 | 0.33 | 0.77 | 12 | empty |
Compared structures
- 6GX9 · Crystal structure of the TNPO3 - CPSF6 RSLD complex · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 6GX9 · Crystal structure of the TNPO3 - CPSF6 rsld complex · an experimental structure of the same protein · chain A against A, TM-score 0.98
- 4OL0 · Crystal structure of transportin-SR2, a karyopherin involved in human disease, in complex… · an experimental structure of the same protein · chain A against B, TM-score 0.89
- 4OL0 · Crystal structure of transportin-SR2, a karyopherin involved in human disease, in complex… · an experimental structure of the same protein · chain A against B, TM-score 0.89
- 4C0O · Transportin 3 in complex with phosphorylated ASF/SF2 · an experimental structure of the same protein · chain A against B, TM-score 0.87
- 4C0O · Transportin 3 in complex with phosphorylated ASF/SF2 · an experimental structure of the same protein · chain A against B, TM-score 0.87
- 4C0Q · Transportin 3 in complex with RAN(Q69L)GTP · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 4C0Q · Transportin 3 in complex with Ran(Q69L)GTP · an experimental structure of the same protein · chain A against A, TM-score 0.85
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y5L0
- Elsewhere: UniProt Q9Y5L0 · AlphaFold DB Q9Y5L0
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