UniProt Q9Y5L0
Transportin-3 (Q9Y5L0)
Transportin-3 (UniProt Q9Y5L0): 11 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 27 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y5L0
- Protein
- Transportin-3
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 27 · 2 records with a druggable one
Structures
12 records of Q9Y5L0 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4C0O | Transportin 3 in complex with phosphorylated ASF/SF2 | x-ray diffraction | A, B | — | — |
| 4C0O | Transportin 3 in complex with phosphorylated ASF/SF2 | x-ray diffraction | A, B | — | — |
| 4C0P | Unliganded Transportin 3 | x-ray diffraction | A, B, C, D | — | — |
| 4C0P | Unliganded transportin 3 | x-ray diffraction | A, B, C, D | — | — |
| 4C0Q | Transportin 3 in complex with Ran(Q69L)GTP | x-ray diffraction | A, B | — | — |
| 4C0Q | Transportin 3 in complex with RAN(Q69L)GTP | x-ray diffraction | A, B | — | — |
| 4OL0 | Crystal structure of transportin-SR2, a karyopherin involved in human disease, in complex with Ran | x-ray diffraction | B | — | — |
| 4OL0 | Crystal structure of transportin-SR2, a karyopherin involved in human disease, in complex with ran | x-ray diffraction | B | — | — |
| 6GX9 | Crystal structure of the TNPO3 - CPSF6 RSLD complex | x-ray diffraction | A, B | MG, BCN, BEN | — |
| 6GX9 | Crystal structure of the TNPO3 - CPSF6 rsld complex | x-ray diffraction | A, B | MG, BCN, BEN | — |
| 8CMK | Transportin-3 TNPO3 in complex with RSY region of CIRBP | x-ray diffraction | A, B | TSS | 20 (best 0.79) |
| Q9Y5L0 | AlphaFold monomer V2.0 prediction for transportin-3 (Q9Y5L0) | predicted | A | — | 7 (best 0.54) |
Ligands
Experiment against prediction
- 6GX9 chain A against the predicted model Q9Y5L0: TM-score 0.99, RMSD 1.25 Å
- 6GX9 chain A against the predicted model Q9Y5L0: TM-score 0.99, RMSD 1.25 Å
- 6GX9 chain B against the predicted model Q9Y5L0: TM-score 0.98, RMSD 1.39 Å
- 6GX9 chain B against the predicted model Q9Y5L0: TM-score 0.98, RMSD 1.39 Å
- 4OL0 chain B against the predicted model Q9Y5L0: TM-score 0.91, RMSD 3.35 Å
- 4OL0 chain B against the predicted model Q9Y5L0: TM-score 0.91, RMSD 3.35 Å
- 4C0Q chain B against the predicted model Q9Y5L0: TM-score 0.90, RMSD 3.35 Å
- 4C0Q chain B against the predicted model Q9Y5L0: TM-score 0.90, RMSD 3.35 Å
- 4C0Q chain A against the predicted model Q9Y5L0: TM-score 0.90, RMSD 3.61 Å
- 4C0Q chain A against the predicted model Q9Y5L0: TM-score 0.90, RMSD 3.61 Å
Elsewhere
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