AlphaFold monomer V2.0 prediction for tyrosine-protein kinase btk (P35991)

Structure

1 distinct chain.

Compared structures

• 4XI2 · Crystal Structure of an auto-inhibited form of Bruton's Tryrosine Kinase · an experimental structure of the same protein · chain A against A, TM-score 0.47
• 4XI2 · Crystal structure of an auto-inhibited form of BRUTON'S tryrosine kinase · an experimental structure of the same protein · chain A against A, TM-score 0.47
• 8GMB · Crystal structure of the full-length Bruton's tyrosine kinase (PH-TH domain not visible) · an experimental structure of the same protein · chain A against A, TM-score 0.46
• 8S93 · Crystal structure of the PH-TH/kinase complex of Bruton's tyrosine kinase · an experimental structure of the same protein · chain A against A, TM-score 0.45
• 8FF0 · Structure of BTK kinase domain with the second-generation inhibitor tirabrutinib · an experimental structure of the same protein · chain A against A, TM-score 0.40
• 8FD9 · Structure of BTK kinase domain with the second-generation inhibitor acalabrutinib · an experimental structure of the same protein · chain A against A, TM-score 0.40
• 8S9F · Crystal structure of the kinase domain of Bruton's Tyrosine Kinase bound to dasatinib · an experimental structure of the same protein · chain A against A, TM-score 0.35

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P35991
• Elsewhere: UniProt P35991 · AlphaFold DB P35991