MolNFT v1 · #461246 · protein

AlphaFold monomer V2.0 prediction for methylcytosine dioxygenase TET1 (Q3URK3)

Q3URK3: “AlphaFold monomer V2.0 prediction for methylcytosine dioxygenase TET1 (Q3URK3)”. 8 pockets (best druggability 0.70). MolNFT v1 #461246 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q3URK3
Type: protein
Length: 2,007 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x9188600a0FCa2914254C94299b1bd9721Bc4D500
Molecule: Methylcytosine dioxygenase TET1
UniProt: Q3URK3
Pockets: 8 · best druggability 0.70

Structure

1 distinct chain · 12% helix, 5% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Methylcytosine dioxygenase TET1	protein	2007	12% helix, 5% strand	Q3URK3

Pockets

8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	61	0.70	0.97	18	empty
2	358	0.69	0.82	41	empty
3	513	0.63	0.76	57	empty
4	326	0.61	0.78	35	empty
5	105	0.59	0.86	22	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q3URK3
Elsewhere: UniProt Q3URK3 · AlphaFold DB Q3URK3

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