Research workbench
AlphaFold monomer V2.0 prediction for methylcytosine dioxygenase TET1 (Q3URK3)
Analyse AlphaFold monomer V2.0 prediction for methylcytosine dioxygenase TET1 (Q3URK3) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q3URK3
- Type
- protein
- Length
- 2,007 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9188600a0FCa2914254C94299b1bd9721Bc4D500
- Molecule
- Methylcytosine dioxygenase TET1
- UniProt
- Q3URK3
- Pockets
- 8 · best druggability 0.70
Structure
1 distinct chain · 12% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methylcytosine dioxygenase TET1 | protein | 2007 | 12% helix, 5% strand | Q3URK3 |
Pockets
8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 61 | 0.70 | 0.97 | 18 | empty |
| 2 | 358 | 0.69 | 0.82 | 41 | empty |
| 3 | 513 | 0.63 | 0.76 | 57 | empty |
| 4 | 326 | 0.61 | 0.78 | 35 | empty |
| 5 | 105 | 0.59 | 0.86 | 22 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3URK3
- Elsewhere: UniProt Q3URK3 · AlphaFold DB Q3URK3
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